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Effects of Low Level Laser Therapy on Baldness

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Below is an except for a recent study of the effects of low level laser therapy on the treatment of baldness and hair loss.  You can download the complete article here.

The cellular effects of LLLT are being employed in the use of low level laser or light therapy for the treatment of baldness and stimulation of hair growth.

 “Low Level Laser Therapy (LLLT) for hair loss treatment uses the well‐known principal of Photobiostimulation.  Photobiostimulation is the biochemical, non‐thermal effect that results from exposure of living tissue to various dosages of energy at varying wavelengths emitted from low level lasers. A Three‐Phased Western IRG approved study released at the ISHRS (International Society for Hair Restoration Surgeons) in Amsterdam, Netherlands in June 2009 by Dr. Grant F. Koher called Effect of Laser Biostimulation In The Treatment of Female Pattern Hair Loss showed after 52 treatments (26 weeks) 100% of the subjects presenting an upward historical linear trend of hair growth from the beginning to the end of the treatments, 97% of the subjects presented an increased hair count of ≥20%, 77% of the subjects presenting a hair count increase of ≥51%.

 Various studies, including a double blind study submitted to the FDA, have shown a number of mechanisms on how Photo biostimulation effects hair growth. Doctor Michael R. Hamblin, Ph.D., a Principal Investigator at the Wellman Center for Photo Medicine and an Associate Massachusetts General Hospital Professor of Dermatology at the Harvard School of Medicine, recently presented new and updated information on the mechanism of action for “laser biostimulation” at the ISHRS 17t h Annual Scientific Meeting. He states, “Several laboratories, including ours, have reported the generation of intracellular reactive oxygen species (ROS) in the mitochondria of cells during low‐level light therapy (LLLT) and the release of nitric oxide from intracellular binding proteins including cytochrome c oxidase.

 Several redox‐sensitive transcription factors are known, such as NF‐kB and AP1, that are able to initiate transcription of genes involved in protective responses to oxidative stress.

 The cellular effects of LLLT are being employed in the use of low level laser or light therapy for the treatment of baldness and stimulation of hair growth.  Various devices like laser combs and hairdryer‐type hoods are used to deliver red laser light to the scalp and encourage new hair growth in patients with thinning hair. Reduction of cell death in the hair follicle, the increase in the number of follicles in the Anagen phase, and the increase in hair pigmentation, has all been observed.”

 Click here to download the complete PDF.

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