This is a listing of studies beginning in 1964 and culminating in 1997 concerning Low Level Hair Therapy results in both men and women. All of these studies have been published show that LLLT actually retards additional hair loss and in most cases reverses it.
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This is one of the best efficacy studies we have been able to locate concerning Low Level Laser Therapy (LLLT). While the article describes the use of a hair comb, the effect of the lasers on combating the root causes of hair loss would be expected to be less effective than what the ManeGain Hair Restoration Therapy can offer. While this article does not highlight ManeGain’s service directly, it solidly builds the case for LLLT in general. To read this study please click here.
The present investigation details the development of model systems for growing two- and threedimensional human neural progenitor cells within a culture medium facilitated by a time-varying electromagnetic field (TVEMF). The cells and culture medium are contained within a two- or three-dimensional culture vessel, and the electromagnetic field is emitted from an electrode or coil. These studies further provide methods to promote neural tissue regeneration by means of culturing the neural cells in either configuration.
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This study involved a 1 year study of men and women with androgenetic alopecia (male pattern hair loss, MPHL and female pattern hair loss, FPHL). To date, there had never been a long-term (> 1 year) efficacy of low lever laser therapy (LLLT) using this population. This experiment was conducted comparing a laser comb (LDS 100) with a placebo device. Over a period of 6 months, 240 men with MPHL and 80 women with FPHL were randomized to receive LLLT treatment or placebo treatment. Men and women continued in up to 1 year, placebo controlled extension studies. Efficacy was evaluated by hair counts, patient and investigator assessments, and panel review of clinical photographs. The results of this treatment sure durable improvements in scalp hair over 1 year (p < 0.001 versus placebo, all endpoints), while treatment with placebo led to progressive hair loss. The conclusion is that in men with MPHL and in women with FPHL, long-term treatment with LLLT over 1 year was well tolerated, led to durable improvements in scalp hair growth, and slowed the further progression of hair loss that occurred without treatment.
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This study goes into detail of how low level red laser can increase bio-stimulation at the cellular level. It also offers some explanations as to how low level lasers (LLL) effect cells on the molecular level.
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A Journal of Rehabilitation Research & Development report that investigated the effects of electrical stimulation (ES) and laser treatment on wound healing in rats conducted by Erciyes University Medical Faculty, Department of Physical Medicine and Rehabilitation, Kayseri, Turkey. A randomized-controlled trial, conducted at the Experimental and Clinical Research Centre of Erciyes University (Kayseri, Turkey), divided 124 healthy female Swiss-Albino rats into four groups.
It was found that both electrical stimulation and laser treatment can be used successfully in decubitis ulcers and chronic wounds, in combination with conventional therapies such as daily care and debridement of wounds; however, electrical stimulation has more beneficial effects during the inflammatory phase in some parameters than laser treatment.
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Low-Level Laser Therapy is Now a Do-It-Yourself Hair Loss Treatment
NEW YORK (October 16, 2003)- While lasers are best known as high-energy beams of coherent light that can cut through a variety of materials including human tissue, low-energy laser light has been found to be capable of modulating beneficial biologic effects in human, animal and plant cells. The biomodulating effects of low-level laser light on human cells has been adapted to medical uses such as enhanced wound healing and treatment of some types of pain, and to cosmetic uses associated with effects on human skin.
Low-level laser light has also been found to have biomodulating effects on human hair and hair follicles. The effectiveness of low-level laser light in hair restoration was described today by Martin Unger, MD, Toronto, Canada, in a presentation at the 11th Annual Meeting of the International Society of Hair Restoration Surgery (ISHRS). The ISHRS is meeting October 15-19, 2003, at the Marriott Marquis Hotel, New York City.
Clinical studies have shown that low-level laser light is effective both cosmetically and physiologically in hair restoration, Dr. Unger said. The cosmetic effects include improvements in hair sheen and strength, characteristics that enhance the perception of “fullness” in overall hair appearance. Physiologic effects on hair follicles observed in both men and women include (1) prevention of hair loss, and (2) stimulation of hair
regrowth in areas of hair loss. Dr. Unger, a physician hair restoration specialist, is medical director of a firm that makes a hand-held low-level laser therapy device for home use in hair restoration (HairMAX LaserComb, Lexington International, Boca Raton, FL). The device is accepted as a Medical Device in Canada, and advertising is allowed to make therapeutic claims that it (1) increases strength of scalp hair in men and women, (2)
prevents scalp hair loss in men and women, and (3) causes regrowth of scalp hair in men and women. In the United States it is accepted by the Food and Drug Administration (FDA) for use as a Cosmetic Laser Product.
Approval by the FDA as a Medical Device is pending while appropriate clinical trials are completed. The device is also sold in other countries outside North America.
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This study shows the effect of low-power laser irradiation on the proliferation activity of cells irradiated by a 830 nm semiconductor BTL-10 laser in a continuous or pulsed mode at an energy density ranging from 2 to 99 J/cm2 (power output, 72 to 360 mW). The irradiated cells were incubated and their proliferation activity was assessed by the MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) assay at 24, 48, 72 and 96 h. In comparison with the control populations, the irradiated cells showed a significant increase in proliferation, regardless of the energy density used, at 72 and 96 h but not at 24 and 48 h. In addition, the stimulation of proliferation was related to the mode of irradiation. The cells irradiated in the pulsed mode (5 000 Hz) showed a higher proliferation activity than the cells treated by continuous laser light. It is concluded that low-power lasers stimulate HeLa cell proliferation.
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